The emergency services are at the scene of a crash on the N25 between Waterford and New Ross.
The incident is believed to have happened outside about a mile outside New Ross on the Waterford side.
The AA says a truck has overturned and Gardai are directing traffic following the incident.
Traffic is impacted in both directions.
Gardai are asking motorists to avoid the area as it will be a number of hours before the road is fully re-opened.
#KILKENNY Overturned truck on N25. More here: https://t.co/ipFDM8svNY
— AA Roadwatch (@aaroadwatch) February 17, 2018